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Author
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Date
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Paper Title
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Keywords
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Jie Wang et al.
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2022
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Characterization of anti-CD79b/CD3 bispecific antibody, a potential therapy for B cell malignancies
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CD79b, bispecific, T cell engager, non-hodgkin lymphoma, immunotherapy
|
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Takeda, Maki et al.
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2021
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Elimination of residual undifferentiated induced pluripotent stem cells (iPSCs) using irradiation for safe clinical applications of iPSC-derived cardiomyocytes
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human induced pluripotent stem cells; Irradiation; Stem cell therapy; Tumorigenicity.
|
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M. Ito, et al.
|
2008
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Antigen-Specific Antibody Production of Human B Cells in NOG Mice Reconstituted with the Human Immune System
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B cell, IgG antibody, HSC, humanized
|
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Yujeong Her, et al.
|
2022
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Development of humanized patient-derived xenograft models for triple negative breast cancer
|
|
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Yili Chen, et al.
|
2021
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A bispecific antibody targeting HER2 and PD-L1 inhibits
tumor growth with superior efficacy
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HER2/PD-L1, BsAbs, ductal carcinoma, gastric carcinoma, PBMCs, humanized
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Shoichi Iriguchi, et al.
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2020
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A clinically applicable and scalable method to regenerate T-cells from iPSCs for off-the-shelf T-cell immunotherapy
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CAR-T, iPSC-derived T cell,
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Tea Soon Park, et al.
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2020
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Vascular progenitors generated from tankyrase inhibitor-regulated naïve diabetic human iPSC potentiate efficient revascularization of ischemic retina
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Naïve diabetic vascular progenitors (N-DVP), hiPSC,
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Daisuke Doi, et al.
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2020
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Pre-clinical study of induced pluripotent stem cell-derived dopaminergic progenitor cells for Parkinson’s disease
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dopaminergic progenitors (DAPs) , iPSC-derived, Parkinson's disease, safety and efficacy assessment
|
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Michael J. Giffin, et al.
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2021
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AMG 757, a Half-Life Extended, DLL3-Targeted Bispecific T-Cell Engager, Shows High Potency and Sensitivity in Preclinical Models of Small-Cell Lung Cancer
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BiTE, SCLC, DLL3, PDX, PBMCs, humanized
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(VR)Guojuan Miao, et al.
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2021
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Development of a novel anti-B7-H4 antibody enhances anti-tumor immune response of human T cells
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B7-H4, antibody, pan T cell, humanized, combined therapy
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|
Hirotoshi Akane, et al.
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2021
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Spontaneous granulocytic leukemia in a NOD/Shi-scid IL-2Rγnull mouse
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granulocytic leukemia, spontaneous tumor
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Chie Kato, et al.
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2009
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Spontaneous thymic lymphomas in the non-obese diabetic/Shi-scid, IL-2Rgnull mouse
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spontaneous thymic lymphoma, T cell
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Yang Gao, et al.
|
2021
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Patient-Derived Xenograft Models for Intrahepatic Cholangiocarcinoma and Their Application in Guiding Personalized Medicine
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intrahepatic cholangiocarcinoma, PDX, lenvatinib
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Yuji Yamashita, et al.
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2021
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Data on long-term survival of the NOD/Shi-scid IL-2Rγ null (NOG) mouse in two facilities
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survival rate, histopathology, tumorigenicity
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Shahrokh Abdolahi, et al.
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2021
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Adaptive NK Cell Therapy Modulated by Anti-PD-1 Antibody in Gastric Cancer Model
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NK cell therapy, anti-PD-1 antibody, gastric cancer
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|
Yoichi Shida, et al.
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2021
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Ex Vivo Expanded and Activated Natural Killer Cells Prolong the Overall Survival of Mice with Glioblastoma-like Cell-Derived Tumors
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NK cell therapy, PD-1/PD-L1, glioblastoma
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N Ahmadbeigi, et al.
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2021
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Characterization of a xenograft model for anti-CD19 CAR T cell studies
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CAR-T cells, Raji cells, lymphoma, inoculation routes
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Ayaka Hara, et al.
|
2021
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CD1d expression in glioblastoma is a promising target for NKT cell-based cancer immunotherapy
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CD1d, iNKT cells, glioblastoma
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|
Sebastian Kollmann, et al.
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2021
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A STAT5B-CD9 axis determines self-renewal in hematopoietic and leukemic stem cells
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HSCs
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Xueliang Gao, et al.
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2021
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Nuclear PFKP promotes CXCR4 dependent T cell acute lymphoblastic leukemia infiltration.
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CDX, T cell acute lymphoblastic leukemia (T-ALL), CXCR4
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Jianshui Zhang, et al.
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2021
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Human Microglia Extensively Reconstitute in Humanized-BLT Mice With Human Interleukin-34 Transgene and Support HIV-1 Brain Infection.
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Humanized bone marrow-liver-thymic mouse (hu-BLT mouse), macroglia, HIV-1, central nervous system (CNS),
|
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Camilla Bjørnbak Holst, et al.
|
2021
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Plasma IL-8 and ICOSLG as prognostic biomarkers in glioblastoma
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glioblastoma, IL-8,ICOS ligand,biomarker, CDX
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Malene Bredahl Hansen, et al.
|
2021
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Identification of lysosome-targeting drugs with anti-inflammatory activity as potential invasion inhibitors of treatment resistant HER2 positive cancers.
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HER2/ErbB2, CDX, ovarian cancer
|
|
Helle Samdal, et al.
|
2021
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Establishment of a Patient-Derived Xenograft Model of Colorectal Cancer in CIEA NOG Mice and Exploring Smartfish Liquid Diet as a Source of Omega-3 Fatty Acids.
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PDX, colorectal cancer
|
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Wei Dai, et al.
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2021
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Activation of transmembrane receptor tyrosine kinase DDR1-STAT3 cascade by extracellular matrix remodeling promotes liver metastatic colonization in uveal melanoma
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DDR1, TGF-β, uveal melanoma (UM), CDX, metastasis
|
|
Haiqing Ni, et al.
|
2021
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Combined strategies for effective cancer immunotherapy with a novel anti-CD47 monoclonal antibody
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CD47, CD20, VEGF-A, mAbs, acute myeloid leukemia (AML), PBMCs, humanized
|
|
Haiping Jiang, et al.
|
2021
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PD-L1/LAG-3 bispecific antibody enhances tumor-specific immunity
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PD-L1, LAG-3, bsAbs, melanoma, PBMCs, humanized, cancer immunotherapy
|
|
Qingming Wang, et al.
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2021
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A transgene-encoded truncated human epidermal growth factor receptor for depletion of anti- B-cell maturation antigen CAR-T cells
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chimeric antigen receptor (CAR), B-cell maturation antigen (BCMA), adoptive T-cell therapy (ACT), truncated human EGFR (eEGFR), multiple myeloma (MM), CDX
|
|
Yongliang Liu, et al.
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2021
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CD9, a potential leukemia stem cell marker, regulates drug resistance and leukemia development in acute myeloid leukemia
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acute myeloid leukemia (AML), CD9, PDX, humanized
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Yosuke Nagesawa, et al.
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2021
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Human osteoclastogenesis in Epstein-Barr virus-induced erosive arthritis in humanized NOD/Shi-scid/IL-2Rγnull mice.
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autoimmune, Epstein-Barr virus, HSCs, humanized
|
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Saori Igura, et al.
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2020
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Pathological study of tubular aggregates occurring spontaneously in the skeletal muscles of non-obese diabetic/Cg -Prkdc scid Il2rgt m1sug /ShiJic (NOG) mice
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sarcoplasmic reticulum, skeletal muscle, tubular aggregate
|
|
Paul Savage, et al.
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2020
|
Chemogenomic profiling of breast cancer patient-derived xenografts reveals targetable vulnerabilities for difficult-to-treat tumors.
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PDX, breast cancer
|
|
Elly L van der Veen, et al.
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2020
|
Zr-pembrolizumab biodistribution is influenced by PD-1-mediated uptake in lymphoid organs.
|
melanoma, PD-1, mAb, CDX, HSCs, humanized
|
|
Wanlu Cao, et al.
|
2020
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LGR5 marks targetable tumor-initiating cells in mouse liver cancer
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LGR5, liver cancer, allograft tumor model
|
|
Mari I. Suominen, et al.
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2020
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A clear increase in TILs and modest tumor growth inhibition by pembrolizumab in prostate cancer tumors growing in bone of CD34+ engrafted NOG mice
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prostate cancer bone metastasis, anti-PD-1, HSCs, humanized
|
|
Zhihui Kuang, et al.
|
2020
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A Novel Bispecific Antibody with PD-L1-assisted OX40 Activation for Cancer Treatment
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PD-L1, OX40, CD134, bsAbs, PBMC, colon cancer, lung cancer, humanized
|
|
Linlin Ma, et al.
|
2020
|
Preclinical development of a novel CD47 nanobody with less toxicity and enhanced anti-cancer therapeutic potential
|
CD47/SIRPα, CD20, CD47, bsAbs, lymphoma
|
|
Yan Wang, et al.
|
2020
|
Tumor-selective blockade of CD47 signaling with a CD47/PD-L1 bispecific antibody for enhanced anti-tumor activity and limited toxicity
|
CD47, PD-L1, bsAbs, SIRPα
|
|
Run Lin, et al.
|
2020
|
Fatty Acid Oxidation Controls CD8+ Tissue-Resident Memory T-cell Survival in Gastric Adenocarcinoma
|
PD-L1, gastric adenocarcinoma, tissue-resident memory T cells (Trm), PDX, humanized
|
|
Kun Zhang, et al.
|
2020
|
Nonclinical safety, tolerance and pharmacodynamics evaluation for meplazumab treating chloroquine-resistant Plasmodium falciparum
|
CD147, safety, toxicology, RBC, Plasmodium falciparum, humanized
|
|
Stijn JH Waaijer, et al.
|
2020
|
Preclinical PET imaging of bispecific antibody ERY974 targeting CD3 and glypican 3 reveals that tumor uptake correlates to T cell infiltrate.
|
CD3, glypican 3(GPC3), bsAbs, hepatocellular carcinoma, ovarian clear cell carcinoma, HSCs, humanized
|
|
Angelique Sao-Mai Sy Do, et al.
|
2020
|
CD133 mRNA-Loaded Dendritic Cell Vaccination Abrogates Glioma Stem Cell Propagation in Humanized Glioblastoma Mouse Model.
|
dendritic cell vaccine, CD133, glioblastoma, HSCs, humanized
|
|
Shinya Rai, et al.
|
2020
|
Chlorpromazine eliminates acute myeloid leukemia cells by perturbing subcellular localization of FLT3-ITD and KIT-D816V
|
acute myeloid leukemia (AML), PDX
|
|
Jennifer Y.Ge, et al.
|
2020
|
Acquired resistance to combined BET and CDK4/6 inhibition in triple-negative breast cancer
|
triple-negative breast cancer (TNBC), CDK4/6 inhibitor, BET inhibitor, CDX
|
|
Ping He, et al.
|
2020
|
Co-expressing LRP6 With Anti-CD19 CAR-T Cells for Improved Therapeutic Effect Against B-ALL
|
CAR-T cells, T memory cell, B-cell ALL
|
|
Elin M. V. Forsberg, et al.
|
2019
|
HER2 CAR-T Cells Eradicate Uveal Melanoma and T-cell Therapy–Resistant Human Melanoma in IL2 Transgenic NOD/SCID IL2 Receptor Knockout Mice
|
melanoma,HER2, CAR-T, ACT,
|
|
Walid Warda, et al.
|
2019
|
CML Hematopoietic Stem Cells Expressing IL1RAP Can Be Targeted by Chimeric Antigen Receptor–Engineered T Cells
|
chronic myeloid leukemia (CML), IL1RAP, CAR-T, HSCs, humanized
|
|
Xiaofang Guo, et al.
|
2019
|
The Preconditioning of Busulfan Promotes Efficiency of Human CD133+ Cells Engraftment in NOD Shi-SCID IL2Rγcnull (NOG) Mice via Intra-Bone Marrow Injection
|
CD133+ stem cell, hematopoietic differenciation, humanized
|
|
Jie Wang, et al.
|
2019
|
Durable blockade of PD-1 signaling links preclinical efficacy of sintilimab to its clinical benefit
|
PD-1,PBMC, receptor occupancy, humanized
|
|
Jing Zhang, et al.
|
2019
|
Transcriptional inhibition by CDK7/9 inhibitor SNS-032 abrogates oncogene addiction and reduces liver metastasis in uveal melanoma
|
cyclin-dependent kinase 7/9 (CDK7/9) inhibitor, uveal melanoma (UM), CDX, metastasis
|
|
Cedric Darini, et al.
|
2019
|
An integrated stress response via PKR suppresses HER2+ cancers and improves trastuzumab therapy
|
HER2, PKR, gastric cancer, PDX
|
|
Thi Bui, et al.
|
2018
|
Enhanced proliferation and effector functions of human immune cells in response to immune checkpoint therapy of MDA-MB-231 tumor bearing huNOG mice engrafted with human CD34+ cells
|
immune check point therapy, PD-1, CTLA-4, breast cancer, HSCs, humanized
|
|
Berglind O.Einasdottir, et al.
|
2018
|
A patient-derived xenograft pre-clinical trial reveals treatment responses and a resistance mechanism to karonudib in metastatic melanoma
|
metastatic melanoma, PDX, T cell
|
|
Tiina E. Kähkönen, et al.
|
2018
|
Cancer-Induced Osteoblastic Bone Growth in a Humanized Mouse Model without Affecting Normal Bone
|
breast cancer, HSCs, humanized
|
|
Sarah L. Buchan, et al.
|
2018
|
Antibodies to Costimulatory Receptor 4-1BB Enhance Anti-tumor Immunity via T Regulatory Cell Depletion and Promotion of CD8 T Cell Effector Function.
|
4-1BB, treg cell, PD-1, combined therapy, PBMCs, humanized
|
|
Weiling He, et al.
|
2017
|
CD155T/TIGIT Signaling Regulates CD8+ T-cell Metabolism and Promotes Tumor Progression in Human Gastric Cancer
|
PBMCs, humanized, gastric cancer, CD155T/TIGIT, anti-PD-1 mAbs
|
|
Qing Zhang, et al.
|
2017
|
Chimeric antigen receptor-modified T Cells inhibit the growth and metastases of established tissue factor-positive tumors in NOG mice
|
chimeric antigen receptor (CAR), T cell, lung cancer, melanoma
|
|
Masahiko Yasuda, et al.
|
2017
|
Incidence of spontaneous lymphomas in non-experimental NOD/Shi-scid, IL-2Rγ null (NOG) mice
|
thymic lymphoma, spontaneous
|
|
R.Ito, et al.
|
2016
|
A Novel Xenogeneic Graft-Versus-Host Disease Model for Investigating the Pathological Role of Human CD4+ or CD8+ T Cells Using Immunodeficient NOG Mice
|
GvHD, CD4+T cell, CD8+T cell, Th17
|
|
B.C.Martel, et al.
|
2015
|
Human Atopic Dermatitis Skin-derived T Cells can Induce a Reaction in Mouse Keratinocytes in vivo
|
atopic dermatitis (AD), skin-infiltrating T cells, keratinocytes
|
|
A Kitadate, et al.
|
2015
|
MicroRNA-16 mediates the regulation of a senescence–apoptosis switch in cutaneous T-cell and other non-Hodgkin lymphomas
|
primary cutaneous T-cell lymphoma (CTCL), non-Hodgkin T/NK-cell lymphoma, CDX
|
|
Zhu A Wang, et al.
|
2014
|
Luminal cells are favored as the cell of origin for prostate cancer.
|
prostate cancer, luminal cell, basal cell, CDX,
|
|
Nicholas Veomatt, et al.
|
2014
|
Therapeutic Efficacy of an Fc-Enhanced TCR-like Antibody to the Intracellular WT1 Oncoprotein
|
leukemia,CDX, mAbs
|
|
Hirotomo Nakata, et al.
|
2005
|
Potent Anti-R5 Human Immunodeficiency Virus Type 1 Effects of a CCR5 Antagonist, AK602/ONO4128/GW873140, in a Novel Human Peripheral Blood Mononuclear Cell Nonobese Diabetic-SCID, Interleukin-2 Receptor γ-Chain-Knocked-Out AIDS Mouse Model
|
HIV,PBMCs
|
|
Mamoru Ito, et al.
|
2002
|
NOD/SCID/gamma(c)(null) mouse: an excellent recipient mouse model for engraftment of human cells.
|
HSCs, humanized
|
|
Yuki Saito, et al.
|
2002
|
The in vivo development of human T cells from CD34(+) cells in the murine thymic environment.
|
HSCs, humanized
|
|
Takashi Yahata, et al.
|
2002
|
Functional human T lymphocyte development from cord blood CD34+ cells in nonobese diabetic/Shi-scid, IL-2 receptor gamma null mice.
|
HSCs, humanized
|
|
|
2002
|
Complete reconstitution of human lymphocytes from cord blood CD34+ cells using the NOD/SCID/gammacnull mice model
|
|
